Gene panel sequencing (NGS) presents the likelihood to research uncommon types of monogenic diabetes (MgD). To that finish, 18 genes had been analyzed in 1676 sufferers referred for MODY genetic testing.Among the many 307 sufferers with a molecular prognosis of MgD, 55 (17.9%) had been mutated in a gene related to a genetic syndrome.
Eight % (n=25) of the sufferers with mutations carried the m.3243A>G variant related to MIDD (Maternally inherited diabetes and deafness). At time of referral little or no had reported listening to loss or some other component of the everyday syndromic presentation.
Six % of the sufferers had been mutated in HNF1B regardless that the everyday extra-pancreatic options weren’t identified at time of referral. Surprisingly the third most distinguished etiology in these uncommon types was the WFS1 gene accounting for two.9% of the sufferers with pathogenic mutations (n=9).
None of them depicted a Wolfram syndrome presentation regardless that some options had been reported in 6/9 sufferers.Proscribing the evaluation of sure genes to sufferers with the respective particular phenotypes would miss out these with partial shows.
These outcomes subsequently underlie the undisputable good thing about NGS methods regardless that the scenario implies cascade penalties each for the molecular biologist and the clinician. Unbiased determinants of cIMT in keeping with the regression fashions had been solely gender sort of glucose monitoring and central systolic BP (cSBP).

Syntaxin Four enrichment in β-cells prevents conversion to autoimmune diabetes in non-obese diabetic (NOD) mice

Syntaxin 4 (STX4), a plasma membrane-localized SNARE protein, regulates human islet β-cell insulin secretion and preservation of β-cell mass. We discovered that human sort 1 diabetic (T1D) and non-obese diabetic (NOD) mouse islets present decreased β-cell STX4 expression, in line with decreased STX4 expression as a possible driver of T1D phenotypes.
Of NOD-iβSTX4 mice, 73% had sustained normoglycemia versus <20% of management NOD (NOD-Ctrl) mice, by 25 weeks of age. At 12 weeks of age, previous to diabetes conversion, NOD-iβSTX4 mice demonstrated superior whole-body glucose tolerance and β-cell glucose responsiveness than NOD-Ctrl mice.
Greater β-cell mass and decreased β-cell apoptosis had been additionally detected in NOD-iβSTX4 pancreata in contrast with these of NOD-Ctrl mice. To check this speculation, we generated inducible β-cell-specific STX4-expressing NOD mice.
Single-cell RNA-sequencing revealed that islets from NOD-iβSTX4 had markedly decreased IFNγ signaling and TNFα signaling by way of NF-ĸB in islet β-cells, together with decreased expression of the chemokine CCL5; CD4+ Treg cells had been additionally enriched in NOD-iβSTX4 islets.
These outcomes present a deeper mechanistic understanding of STX4 perform in β-cell safety and warrant additional investigation of STX4 enrichment as a technique to reverse or forestall T1D in people or defend β-cell grafts.
This was a cross-sectional case-control examine. In complete, 192 sufferers and 188 wholesome controls had been enrolled from the Pediatric Diabetes Clinic at King Salman Navy Hospital between January 2000 and December 2010. Detailed sufferers’ information recorded whereas distributing questionnaires to regulate samples included varied gradations of consanguinity and household histories of T1DM and autoimmune illness.

No consensus was discovered within the Swedish tips for any of the 31 variables. Some tips had been contradictory. The being pregnant tips had been adopted in 17.5% of the medical data, 18.4% adopted the labor tips, and 5.3% adopted each tips. The onset of labor, mode of supply and HbA1c within the third trimester different considerably, relying on the adherence to tips.

Steady Blood Glucose Monitoring Will increase Vigorous Bodily Exercise Ranges and Is Related With Diminished Hypoglycemia Avoidance Habits In Youth With Kind 1 Diabetes

The first purpose of this examine was to discover bodily exercise (PA) ranges, hypoglycemia concern scores and hypoglycemia episodes in keeping with insulin administration and blood glucose monitoring strategies in youth with sort 1 diabetes (T1D). A self-administered questionnaire was accomplished by 28 kids and 33 adolescents with T1D, and their PA was assessed.

Hypoglycemia episodes, concern of hypoglycemia scores, insulin remedy (pump vs. injection) and blood glucose monitoring (steady blood glucose screens [CGMs] vs. blood glucose meters) strategies are reported within the current work.

There have been no vital variations within the variety of hypoglycemic episodes, little one hypoglycemia concern survey conduct or complete scores, or any elements of the PA profile between youth utilizing injections and people utilizing a pump. CGM use correlated considerably with VPA ranges (β=0.6; p=0.04).

Greater VPA ranges had been related to larger little one hypoglycemia concern survey conduct scores (β=0.52; p=0.04). The latter correlates negatively with the variety of episodes of hypoglycemia previously 12 months in all class teams. The kind of insulin injection was not related to extra exercise in youth with T1D.

In distinction, CGM use could also be related to elevated vigorous PA amongst T1D youth. These with larger hypoglycemia concern survey conduct scores engaged in additional VPA and had fewer hypoglycemia episodes. Though CGM use ensures steady monitoring of glycemia throughout train, growing hypoglycemia avoidance conduct remains to be a crucial a part of train administration methods in energetic youth with T1D.

Central Systolic Blood Strain Is Related With Early Vascular Harm in Kids and Adolescents With Kind 1 Diabetes

Carotid intima-media thickness (cIMT), carotid distensibility coefficient (cDC), and carotid-femoral pulse wave velocity (PWV) had been measured in kids and adolescents with T1D, in a follow-up on the outpatient clinics of Verona.

Blood strain (BP; each central and peripheral), metabolic and different cardiovascular threat components had been evaluated in multivariate linear regressions to evaluate the affiliation with the measured indices of subclinical vascular injury.

100 and twenty-six kids and adolescents had been included. cIMT was above the 95th percentile for age and top in 60.8% of the inhabitants, whereas 26% of the pattern had cDC impairment (lower than the fifth percentile) and 4.8% had an elevated PWV.

PWV was related to age, intercourse, coronary heart charge, and cSBP; cDC with age and each cSBP and, alternatively, peripheral BP (pBP). Neither pBP nor any of the examined metabolic parameters, together with glycated hemoglobin, was related to PWV and cIMT.

RRAD Antibody

1-CSB-PA248209
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against RRAD. Recognizes RRAD from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:5000, IHC:1:25-1:100

RRAD Antibody

1-CSB-PA003910
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against RRAD. Recognizes RRAD from Human. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/20000

RRAD Antibody

1-CSB-PA779820
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against RRAD. Recognizes RRAD from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200

RRAD Antibody

37229-100ul 100ul
EUR 252

Anti-RRAD (aa36-48) antibody

STJ72757 100 µg
EUR 359

Rrad/ Rat Rrad ELISA Kit

ELI-14921r 96 Tests
EUR 886

Polyclonal RRAD Antibody

APR05556G 0.1ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human RRAD . This antibody is tested and proven to work in the following applications:

RRAD Conjugated Antibody

C37229 100ul
EUR 397

RRAD siRNA

20-abx932133
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

RRAD Blocking Peptide

33R-4793 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of RRAD antibody, catalog no. 70R-5797

RRAD Blocking Peptide

33R-10070 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of RRAD antibody, catalog no. 70R-5798

RRAD Blocking Peptide

20-abx063234
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

RRAD ELISA KIT|Human

EF005507 96 Tests
EUR 689

RRAD Recombinant Protein (Human)

RP095493 100 ug Ask for price

RRAD Recombinant Protein (Mouse)

RP169340 100 ug Ask for price

RRAD Recombinant Protein (Rat)

RP226925 100 ug Ask for price

Human RRAD shRNA Plasmid

20-abx954199
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

GTP-Binding Protein RAD (RRAD) Antibody

abx432011-200ul 200 ul
EUR 384

GTP-binding protein RAD (RRAD) Antibody

20-abx241706
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

GTP-binding protein RAD (RRAD) Antibody

20-abx214509
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

GTP-binding protein RAD (RRAD) Antibody

abx332370-100ul 100 ul
EUR 425

GTP-binding protein RAD (RRAD) Antibody

20-abx324872
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

GTP-Binding Protein RAD (RRAD) Antibody

20-abx008742
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

Rrad ORF Vector (Rat) (pORF)

ORF075643 1.0 ug DNA
EUR 506

RRAD ORF Vector (Human) (pORF)

ORF031832 1.0 ug DNA
EUR 405

Rrad ORF Vector (Mouse) (pORF)

ORF056448 1.0 ug DNA
EUR 506

Polyclonal RRAD (aa36-48) Antibody (internal region)

APG00807G 0.1mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human RRAD (aa36-48) (internal region). This antibody is tested and proven to work in the following applications:

Rrad sgRNA CRISPR Lentivector set (Rat)

K7052701 3 x 1.0 ug
EUR 339

RRAD sgRNA CRISPR Lentivector set (Human)

K2069901 3 x 1.0 ug
EUR 339

Rrad sgRNA CRISPR Lentivector set (Mouse)

K3480701 3 x 1.0 ug
EUR 339

RRAD And GEM Like GTPase 2 (REM2) Antibody

abx122938-100ug 100 ug
EUR 391

RRAD And GEM Like GTPase 2 (REM2) Antibody

abx237237-100ug 100 ug
EUR 551

RRAD 3'UTR Luciferase Stable Cell Line

TU022380 1.0 ml
EUR 1394

Rrad 3'UTR Luciferase Stable Cell Line

TU118183 1.0 ml Ask for price

Rrad 3'UTR GFP Stable Cell Line

TU168183 1.0 ml Ask for price

Rrad 3'UTR Luciferase Stable Cell Line

TU219725 1.0 ml Ask for price

Rrad 3'UTR GFP Stable Cell Line

TU269725 1.0 ml Ask for price

RRAD 3'UTR GFP Stable Cell Line

TU072380 1.0 ml
EUR 1394

RRAD Protein Vector (Human) (pPB-C-His)

PV127326 500 ng
EUR 552

RRAD Protein Vector (Human) (pPB-N-His)

PV127327 500 ng
EUR 552

RRAD Protein Vector (Human) (pPM-C-HA)

PV127328 500 ng
EUR 552

RRAD Protein Vector (Human) (pPM-C-His)

PV127329 500 ng
EUR 552

RRAD Protein Vector (Rat) (pPB-C-His)

PV302570 500 ng
EUR 603

RRAD Protein Vector (Rat) (pPB-N-His)

PV302571 500 ng
EUR 603

RRAD Protein Vector (Rat) (pPM-C-HA)

PV302572 500 ng
EUR 603

RRAD Protein Vector (Rat) (pPM-C-His)

PV302573 500 ng
EUR 603

RRAD Protein Vector (Mouse) (pPB-C-His)

PV225790 500 ng
EUR 603

RRAD Protein Vector (Mouse) (pPB-N-His)

PV225791 500 ng
EUR 603

RRAD Protein Vector (Mouse) (pPM-C-HA)

PV225792 500 ng
EUR 603

RRAD Protein Vector (Mouse) (pPM-C-His)

PV225793 500 ng
EUR 603

Rrad sgRNA CRISPR Lentivector (Rat) (Target 1)

K7052702 1.0 ug DNA
EUR 154

Rrad sgRNA CRISPR Lentivector (Rat) (Target 2)

K7052703 1.0 ug DNA
EUR 154

Rrad sgRNA CRISPR Lentivector (Rat) (Target 3)

K7052704 1.0 ug DNA
EUR 154

RRAD sgRNA CRISPR Lentivector (Human) (Target 1)

K2069902 1.0 ug DNA
EUR 154

RRAD sgRNA CRISPR Lentivector (Human) (Target 2)

K2069903 1.0 ug DNA
EUR 154

RRAD sgRNA CRISPR Lentivector (Human) (Target 3)

K2069904 1.0 ug DNA
EUR 154

Rrad sgRNA CRISPR Lentivector (Mouse) (Target 1)

K3480702 1.0 ug DNA
EUR 154

Rrad sgRNA CRISPR Lentivector (Mouse) (Target 2)

K3480703 1.0 ug DNA
EUR 154

Rrad sgRNA CRISPR Lentivector (Mouse) (Target 3)

K3480704 1.0 ug DNA
EUR 154

Mouse GTP- binding protein RAD, Rrad ELISA KIT

ELI-14089m 96 Tests
EUR 865

Human GTP- binding protein RAD, RRAD ELISA KIT

ELI-35549h 96 Tests
EUR 824

RRAD Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)

LV658369 1.0 ug DNA
EUR 514

RRAD Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)

LV658373 1.0 ug DNA
EUR 514

RRAD Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)

LV658374 1.0 ug DNA
EUR 514

Rat GTP-binding protein RAD (RRAD) ELISA Kit

abx391893-96tests 96 tests
EUR 911

Mouse GTP-binding protein RAD (RRAD) ELISA Kit

abx390415-96tests 96 tests
EUR 911

Human GTP-binding protein RAD (RRAD) ELISA Kit

abx385354-96tests 96 tests
EUR 911

Rrad ELISA Kit| Rat GTP-binding protein RAD ELISA Kit

EF019253 96 Tests
EUR 689

Rrad ELISA Kit| Mouse GTP-binding protein RAD ELISA Kit

EF016057 96 Tests
EUR 689

Rrad sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)

K7052705 3 x 1.0 ug
EUR 376

RRAD sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K2069905 3 x 1.0 ug
EUR 376

Rrad sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K3480705 3 x 1.0 ug
EUR 376

Human RRAD And GEM Like GTPase 2 (REM2) ELISA Kit

abx382769-96tests 96 tests
EUR 911

RRAD Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)

LV658370 1.0 ug DNA
EUR 514

RRAD Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV658371 1.0 ug DNA
EUR 572

RRAD Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

LV658372 1.0 ug DNA
EUR 572

Rrad sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)

K7052706 1.0 ug DNA
EUR 167

Rrad sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)

K7052707 1.0 ug DNA
EUR 167

Rrad sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)

K7052708 1.0 ug DNA
EUR 167

RRAD sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K2069906 1.0 ug DNA
EUR 167

RRAD sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

K2069907 1.0 ug DNA
EUR 167

RRAD sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

K2069908 1.0 ug DNA
EUR 167

Rrad sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K3480706 1.0 ug DNA
EUR 167

Rrad sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K3480707 1.0 ug DNA
EUR 167

Rrad sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K3480708 1.0 ug DNA
EUR 167

Anti-Anti-SEPT2 Antibody antibody

STJ25475 100 µl
EUR 277

Anti-Anti-SEPT5 Antibody antibody

STJ25477 100 µl
EUR 277
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody

STJ25479 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT2 Antibody antibody

STJ28365 100 µl
EUR 277

Anti-Anti-SEPT7 Antibody antibody

STJ28963 100 µl
EUR 277
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody

STJ117206 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT12 Antibody antibody

STJ117759 100 µl
EUR 277
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH6 Antibody antibody

STJ118549 100 µl
EUR 277

Anti-Anti-MARCH6 Antibody antibody

STJ118550 100 µl
EUR 277

Anti-Anti-MARCH7 Antibody antibody

STJ118752 100 µl
EUR 277

Anti-Anti-SEPT3 Antibody antibody

STJ118990 100 µl
EUR 277

Anti-Anti-SEPT1 antibody antibody

STJ119580 100 µl
EUR 277
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

Anti-Anti-SEPT7 Antibody antibody

STJ116214 100 µl
EUR 277
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT6 antibody antibody

STJ11100949 100 µl
EUR 277
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody

STJ111369 100 µl
EUR 277
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody

STJ111530 100 µl
EUR 277

Anti-Anti-SEPT4 Antibody antibody

STJ112276 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody

STJ112609 100 µl
EUR 277

Anti-Anti-SEPT11 Antibody antibody

STJ113941 100 µl
EUR 277

Anti-Anti-SEPT11 Antibody antibody

STJ114081 100 µl
EUR 277

Anti-Anti-SEPT5 Antibody antibody

STJ114819 100 µl
EUR 277
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-MARCH8 Antibody antibody

STJ114828 100 µl
EUR 277

Anti-Anti-DDB1 Antibody

A00333 100uL
EUR 455
Description: Rabbit Polyclonal DDB1 Antibody. Validated in IP and tested in Human, Mouse.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-10x96wellstestplate 10x96-wells test plate
EUR 5647.8
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-1x48wellstestplate 1x48-wells test plate
EUR 552.76
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-1x96wellstestplate 1x96-wells test plate
EUR 746.8
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-5x96wellstestplate 5x96-wells test plate
EUR 3060.6
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

4-AEA465Hu
  • EUR 5698.00
  • EUR 3011.00
  • EUR 747.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.

ELISA kit for Human Anti-AsAb (Anti-Anti-Sperm Antibody Antibody)

ELK8071 1 plate of 96 wells
EUR 432
Description: A competitive Inhibition ELISA kit for detection of Anti-Anti-Sperm Antibody Antibody from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Anti- ZNF660 antibody

ABD2410 100 ug
EUR 438

Anti-STAT5B Antibody

A1753-100
EUR 479

Anti-CREB1 Antibody

A1754-100
EUR 479

Anti-COX7B Antibody

A1756-100
EUR 479

Anti-COX6B1 Antibody

A1757-100
EUR 479

Anti-COX7B2 Antibody

A1758-100
EUR 479

Anti-COX19 Antibody

A1759-100
EUR 479

Anti-AIMP2 Antibody

A1760-100
EUR 479

Anti-NFKBIE Antibody

A1762-100
EUR 479

A excessive proportion of early vascular injury, particularly an elevated cIMT, is current in kids and adolescents with T1D in whom cSBP appears to be a standard determinant. In kids and adolescents with T1DM, a particular focus must be on hemodynamic threat components past metabolic ones.

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