Diabetic foot ulcer (DFU) is the most typical and expensive sequela of diabetes mellitus, usually resulting in lower-extremity amputation with poor 5-year survival charges. Staphylococcus aureus is probably the most prevalent pathogen remoted from DFU, suggesting adaptation of S. aureus to the distinctive metabolic situations of diabetes.
Diabetes is a fancy metabolic dysfunction with will increase not solely in serum glucose ranges but in addition in ranges of different sugars, together with fructose, mannose, and glucose-6-phosphate (G6P). Nevertheless, the impact of metabolism of those sugars on the pathogenesis of S. aureus just isn’t totally understood.
On this research, we demonstrated that metabolism of G6P, fructose, and mannose induced larger expression of staphylococcal virulence components than did glucose metabolism, however solely G6P results had been impartial of glucose-mediated carbon catabolite repression, suggesting a physiologically related position in diabetes.
Our in vivo research additional demonstrated that G6P was extremely current in pores and skin adipose tissues of diabetic TALLYHO/JngJ mice, and subcutaneous an infection with S. aureus brought about considerably larger tissue necrosis and bacterial burden, in comparison with nondiabetic SWR/J mice.
Lastly, enhanced pathogenesis of S. aureus in diabetic TALLYHO/JngJ mice was considerably attenuated by deletion of the hexose phosphate transport (HPT) system. These outcomes recommend that G6P is a vital metabolic sign for S. aureus, enhancing the virulence in diabetes. A greater understanding of how G6P metabolism is linked to the virulence of S. aureus will result in the event of novel different therapeutics.
Sugars are important vitamins for S. aureus to outlive and proliferate inside the host. As a result of elevated serum glucose ranges are an indicator of diabetes, most research have targeted on the impact of glucose metabolism, and little or no is thought relating to the consequences of metabolism of different sugars on the pathogenesis of S. aureus in diabetes.
On this research, we demonstrated that G6P, which is very current in diabetes, can induce expression of staphylococcal virulence components that trigger extreme tissue necrosis and bacterial burden in pores and skin infections.
Our outcomes spotlight the significance of dietary management of blood sugar ranges, not solely glucose but in addition different extremely metabolizable sugars similar to G6P. A greater understanding of how activation of the HPT system is linked to the virulence of S. aureus will information growth of novel different therapeutics.
Elements Influencing Change in Serum Uric Acid after Administration of the Sodium-Glucose Cotransporter 2 Inhibitor Luseogliflozin in Sufferers With Kind 2 Diabetes Mellitus
Though sodium-glucose cotransporter 2 (SGLT2) inhibitors decrease serum uric acid, their long-term impact on uric acid metabolism just isn’t properly understood. We analyzed pooled information from research whereby sufferers with sort 2 diabetes mellitus (T2DM) acquired luseogliflozin-an SGLT2 inhibitor.
Upon stratifying sufferers by baseline glycated hemoglobin (HbA1c) or serum uric acid, decrease HbA1c or larger serum uric acid stage was related to a larger discount in serum uric acid after remedy.
At week 12 of remedy, a major enhance in urinary glucose/creatinine (Cr) ratio and urinary uric acid clearance/Cr clearance ratio (CUA /CCr ratio) and a major discount in serum uric acid had been noticed.
Comparability of the subgroups of sufferers with a discount or a rise in serum uric acid confirmed that the rise subgroup had a better estimated glomerular filtration price (eGFR) at baseline, and the eGFR was considerably lowered, related to a major discount within the CUA /CCr ratio.
A number of regression evaluation confirmed that the discount in serum uric acid within the luseogliflozin group was strongly related to baseline excessive serum uric acid, low HbA1c ranges, and a rise in eGFR. Luseogliflozin was proven to scale back serum uric acid by enhancing urinary uric acid excretion in affiliation with elevated urinary glucose.
Therapy with luseogliflozin resulted in elevated serum uric acid in some sufferers, which can be as a result of lowered glomerular filtration of uric acid by way of the tubuloglomerular suggestions. SGLT2 inhibitors lowered serum uric acid desirably in sufferers with T2DM with low HbA1c and excessive serum uric acid. This text is protected by copyright. All rights reserved.
Steroid profiling and genetic variants in Chinese language ladies with gestational diabetes mellitus
Earlier research have demonstrated that steroids had been related to gestational diabetes mellitus (GDM). Nevertheless, outcomes from completely different research remained inconsistent, and solely a restricted vary of steroids had been investigated in these research.
Subsequently, we aimed to investigate complete steroid profiling in Chinese language ladies with GDM throughout third-trimester being pregnant. In 97 Chinese language pregnant ladies, we measured steroid profile utilizing a LC-MS/MS technique, and calculated product-to-precursor ratios in metabolic pathways of steroids.
Then sixteen genetic variants of genes encoding steroidogenic enzymes had been genotyped by MassARRAY system. There have been vital variations (P < 0.05) and apparent modifications (fold change <0.67 or >1.5) in steroids (testosterone, estriol, pregnenolone and dehydroepiandrosterone) and product-to-precursor ratios (E2/T and T/AD) between GDM and management teams.
Hepatic insulin resistance (HIR) is taken into account to be an impartial predictor of metabolic problems and performs an necessary position in systemic irritation, which contributes to abnormalities in heart problems (CVD) threat components.
The purpose of this research was to research the connection between HIR and new markers of cardiovascular dangers, together with leptin/adiponectin ratio (L/A), lipoprotein(a) [Lp(a)], and tumor necrosis issue alpha (TNF-α), at comparable entire physique insulin sensitivity in non-diabetic people with or with out CVD and at excessive threat of growing sort 2 diabetes.
Human Neural cell adhesion molecule L1 protein (L1CAM) |
1-CSB-RP074394h(C) |
Cusabio |
-
EUR 456.00
-
EUR 256.80
-
EUR 1570.80
-
EUR 672.00
-
EUR 1047.60
-
EUR 314.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Human Neural cell adhesion molecule L1 protein(L1CAM),partial expressed in E.coli |
Human Tenascin (TNC) |
1-CSB-RP115094h(C) |
Cusabio |
-
EUR 456.00
-
EUR 256.80
-
EUR 1570.80
-
EUR 672.00
-
EUR 1047.60
-
EUR 314.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Human Tenascin(TNC),partial expressed in E.coli |
Human Antigen KI-67 (MKI67) |
1-CSB-RP116174h(c) |
Cusabio |
-
EUR 456.00
-
EUR 256.80
-
EUR 1570.80
-
EUR 672.00
-
EUR 1047.60
-
EUR 314.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Human Antigen KI-67(MKI67) ,partial expressed in E.coli |
Human Laminin subunit beta-2 (LAMB2) |
1-CSB-RP142794h(c) |
Cusabio |
-
EUR 456.00
-
EUR 256.80
-
EUR 1570.80
-
EUR 672.00
-
EUR 1047.60
-
EUR 314.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Human Laminin subunit beta-2(LAMB2),partial expressed in E.coli |
Helicobacter pylori Vacuolating cytotoxin autotransporter (vacA) |
1-CSB-RP143794Ba(C) |
Cusabio |
-
EUR 733.20
-
EUR 370.80
-
EUR 2192.40
-
EUR 1126.80
-
EUR 1461.60
-
EUR 476.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Helicobacter pylori Vacuolating cytotoxin autotransporter(vacA),partial expressed in E.coli |
Human Glutamyl aminopeptidase (ENPEP) |
1-CSB-RP147594h(c) |
Cusabio |
-
EUR 456.00
-
EUR 256.80
-
EUR 1570.80
-
EUR 672.00
-
EUR 1047.60
-
EUR 314.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Human Glutamyl aminopeptidase(ENPEP),partial expressed in E.coli |
Saccharomyces cerevisiae Trehalose-phosphatase (TPS2) |
1-CSB-RP165694Ye(c) |
Cusabio |
-
EUR 733.20
-
EUR 370.80
-
EUR 2192.40
-
EUR 1126.80
-
EUR 1461.60
-
EUR 476.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Saccharomyces cerevisiae Trehalose-phosphatase(TPS2),partial expressed in E.coli |
Mouse Protein Muc5ac (Muc5ac) |
1-CSB-RP172294m(C) |
Cusabio |
-
EUR 606.00
-
EUR 318.00
-
EUR 2192.40
-
EUR 919.20
-
EUR 1461.60
-
EUR 402.00
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Mouse Protein Muc5ac(Muc5ac),partial expressed in E.coli |
Human Histone deacetylase 7 (HDAC7) |
1-CSB-RP178994h(C) |
Cusabio |
-
EUR 456.00
-
EUR 256.80
-
EUR 1570.80
-
EUR 672.00
-
EUR 1047.60
-
EUR 314.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Human Histone deacetylase 7(HDAC7),partial expressed in E.coli |
Human Telomerase protein component 1 (TEP1) |
1-CSB-RP180494h(c) |
Cusabio |
-
EUR 456.00
-
EUR 256.80
-
EUR 1570.80
-
EUR 672.00
-
EUR 1047.60
-
EUR 314.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Human Telomerase protein component 1(TEP1),partial expressed in E.coli |
Human Collagen alpha-1 (XVII) chain (COL17A1) |
1-CSB-RP180994h(c) |
Cusabio |
-
EUR 456.00
-
EUR 256.80
-
EUR 1570.80
-
EUR 672.00
-
EUR 1047.60
-
EUR 314.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Human Collagen alpha-1(XVII) chain(COL17A1),partial expressed in E.coli |
Saccharomyces cerevisiae Neutral trehalase (NTH1) |
1-CSB-RP181594Ye(c) |
Cusabio |
-
EUR 733.20
-
EUR 370.80
-
EUR 2192.40
-
EUR 1126.80
-
EUR 1461.60
-
EUR 476.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Saccharomyces cerevisiae Neutral trehalase(NTH1),partial expressed in E.coli |
Human Nuclear pore membrane glycoprotein 210 (NUP210) |
1-CSB-EP016195HU(C) |
Cusabio |
-
EUR 456.00
-
EUR 256.80
-
EUR 1570.80
-
EUR 672.00
-
EUR 1047.60
-
EUR 314.40
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
Description: Recombinant Human Nuclear pore membrane glycoprotein 210(NUP210),partial expressed in E.coli |
Diabetes (Type 1) Exosome |
P141-DB1 |
101Bio |
- |
Ask for price |
Diabetes (Type 2) Exosome |
P141-DB2 |
101Bio |
- |
Ask for price |
Diabetes (Type 1) Exosome RNA |
P241-DB1 |
101Bio |
- |
Ask for price |
Diabetes (Type 2) Exosome RNA |
P241-DB2 |
101Bio |
- |
Ask for price |
Custom Antibody titration by ELISA up to 2 rabbits and 1 bleed |
ELISA-1 |
Alpha Diagnostics |
1 |
EUR 242.4 |
Canine C-Peptide ELISA Kit |
DLR-C-Peptide-c-48T |
DL Develop |
48T |
EUR 632.4 |
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Canine C-Peptide ELISA Kit |
DLR-C-Peptide-c-96T |
DL Develop |
96T |
EUR 825.6 |
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Canine C-Peptide ELISA Kit |
RDR-C-Peptide-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 668.4 |
Canine C-Peptide ELISA Kit |
RDR-C-Peptide-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 928.8 |
Canine C-Peptide ELISA Kit |
RD-C-Peptide-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 639.6 |
Canine C-Peptide ELISA Kit |
RD-C-Peptide-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 888 |
Rat Cytochrome-C (Cyt-c) protein WB +ve control |
CYTC11-C |
Alpha Diagnostics |
100 ul |
EUR 343.2 |
Recombinant Borrelia burgdorferi Osp-C protein (OSP-C) control for Western blot |
OSPC12-C |
Alpha Diagnostics |
100 ul |
EUR 343.2 |
Human Apolipoprotein C-I protein control for WB |
APOC11-C |
Alpha Diagnostics |
100 ul |
EUR 343.2 |
Human Apolipoprotein C-II protein control for WB |
APOC22-C |
Alpha Diagnostics |
100 ul |
EUR 343.2 |
Human Apolipoprotein C-III protein control for WB |
APOC32-C |
Alpha Diagnostics |
100 ul |
EUR 343.2 |
Human C-Peptide ELISA Kit |
DLR-C-Peptide-Hu-48T |
DL Develop |
48T |
EUR 477.6 |
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Human C-Peptide ELISA Kit |
DLR-C-Peptide-Hu-96T |
DL Develop |
96T |
EUR 613.2 |
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Mouse C-Peptide ELISA Kit |
DLR-C-Peptide-Mu-48T |
DL Develop |
48T |
EUR 540 |
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Mouse C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Mouse C-Peptide ELISA Kit |
DLR-C-Peptide-Mu-96T |
DL Develop |
96T |
EUR 698.4 |
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Mouse C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Rat C-Peptide ELISA Kit |
DLR-C-Peptide-Ra-48T |
DL Develop |
48T |
EUR 560.4 |
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Rat C-Peptide ELISA Kit |
DLR-C-Peptide-Ra-96T |
DL Develop |
96T |
EUR 726 |
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Human C-Peptide ELISA Kit |
RDR-C-Peptide-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 484.8 |
Human C-Peptide ELISA Kit |
RDR-C-Peptide-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 667.2 |
Mouse C-Peptide ELISA Kit |
RDR-C-Peptide-Mu-48Tests |
Reddot Biotech |
48 Tests |
EUR 558 |
Mouse C-Peptide ELISA Kit |
RDR-C-Peptide-Mu-96Tests |
Reddot Biotech |
96 Tests |
EUR 771.6 |
Rat C-Peptide ELISA Kit |
RDR-C-Peptide-Ra-48Tests |
Reddot Biotech |
48 Tests |
EUR 583.2 |
Rat C-Peptide ELISA Kit |
RDR-C-Peptide-Ra-96Tests |
Reddot Biotech |
96 Tests |
EUR 806.4 |
Human C-Peptide ELISA Kit |
RD-C-Peptide-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 464.4 |
Human C-Peptide ELISA Kit |
RD-C-Peptide-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 638.4 |
Mouse C-Peptide ELISA Kit |
RD-C-Peptide-Mu-48Tests |
Reddot Biotech |
48 Tests |
EUR 535.2 |
Mouse C-Peptide ELISA Kit |
RD-C-Peptide-Mu-96Tests |
Reddot Biotech |
96 Tests |
EUR 738 |
Rat C-Peptide ELISA Kit |
RD-C-Peptide-Ra-48Tests |
Reddot Biotech |
48 Tests |
EUR 558 |
Rat C-Peptide ELISA Kit |
RD-C-Peptide-Ra-96Tests |
Reddot Biotech |
96 Tests |
EUR 771.6 |
Purified Human C-Reactive Protein (CRP) control for WB |
CRP12-C |
Alpha Diagnostics |
100 ul |
EUR 343.2 |
Purified Rat C-Reactive Protein (CRP) control for WB |
CRP16-C |
Alpha Diagnostics |
100 ul |
EUR 343.2 |
Purified Dog C-Reactive Protein (CRP) control for WB |
CRP18-C |
Alpha Diagnostics |
100 ul |
EUR 343.2 |
Recombinant (E.coli) C. perfringens beta toxin protein control for western blot |
CPB12-C |
Alpha Diagnostics |
100 ul |
EUR 343.2 |
Recombinant (E.coli) C. perfringens epsilon toxin protein control for western blot |
CPE13-C |
Alpha Diagnostics |
100 ul |
EUR 343.2 |
Recombinant (E.coli) C. perfringens alpha toxin protein control for western blot |
CPA11-C |
Alpha Diagnostics |
100 ul |
EUR 343.2 |
Recombinant (NS0) purified Mouse C-Reactive Protein (CRP) cotnrol for Western |
CRP21-C |
Alpha Diagnostics |
100 ul |
EUR 343.2 |
Recombinant (NS0) purified Mouse C-Reactive Protein (CRP) cotnrol for Western |
CRP24-C |
Alpha Diagnostics |
100 ul |
EUR 343.2 |
Human recombinant purified His-tag c-myc protein (~65 kda) control |
MYC17-C |
Alpha Diagnostics |
100 ul |
EUR 343.2 |
Multi Fusion-Tagged recombinant Protein 52-Kda containing 16-tags (T-7, HSV, C-myc, VSV-G, Glu-Glu, V5, e-tag, Flag, S-tag, HA, KT3, E2, Au1, Au5, 6xHis-tags) for ELISA/Western |
MFPM52-C |
Alpha Diagnostics |
100 ul |
EUR 343.2 |
Recombinant purified Circumsporozoite (CSP, P.falciparum) C-terminal (207-397 aa) His-tag protein control for Western Blot |
CSPF11-C |
Alpha Diagnostics |
100 ul |
EUR 343.2 |
Recombinant purified his-tag-Protein (~130 kda) control for ELISA |
HISP130-C |
Alpha Diagnostics |
10 ug |
EUR 343.2 |
Cytochrome c (Mitochondrial Marker); Clone 7H8.2C12 (Concentrate) |
RA0359-C.1 |
ScyTek Laboratories |
0.1 ml |
EUR 150 |
Cytochrome c (Mitochondrial Marker); Clone 7H8.2C12 (Concentrate) |
RA0359-C.5 |
ScyTek Laboratories |
0.5 ml |
EUR 360 |
Cytochrome c (Mitochondrial Marker); Clone CTC05 (Concentrate) |
RA0360-C.1 |
ScyTek Laboratories |
0.1 ml |
EUR 150 |
Cytochrome c (Mitochondrial Marker); Clone CTC05 (Concentrate) |
RA0360-C.5 |
ScyTek Laboratories |
0.5 ml |
EUR 360 |
Monkey IgM (Rhesus, non-immune control) for ELISA Kit, 1 ml (target range ~20-30 ug/ml) |
7060-C |
Alpha Diagnostics |
1 ml |
EUR 343.2 |
Tenascin C (Stromal Marker For Epithelial Malignancy); Clone T2H5 (Concentrate) |
RA0135-C.1 |
ScyTek Laboratories |
0.1 ml |
EUR 150 |
Tenascin C (Stromal Marker For Epithelial Malignancy); Clone T2H5 (Concentrate) |
RA0135-C.5 |
ScyTek Laboratories |
0.5 ml |
EUR 296.4 |
Cytokeratin 8/18 (Epithelial Marker); Clone C-43 & DC10 (Concentrate) |
RA0388-C.1 |
ScyTek Laboratories |
0.1 ml |
EUR 150 |
Cytokeratin 8/18 (Epithelial Marker); Clone C-43 & DC10 (Concentrate) |
RA0388-C.5 |
ScyTek Laboratories |
0.5 ml |
EUR 360 |
Multi Fusion-Tagged Protein Marker containing 5 tags (His, T7, Myc, HA, VSV-G tags) Protein (Pure ~20 Kda) for ELISA/Western |
MFPM20-C |
Alpha Diagnostics |
100 ul |
EUR 343.2 |
HER-2 / c-erbB-2 / neu / CD340; Clone HRB2/451 (Concentrate) |
RA0108-C.1 |
ScyTek Laboratories |
0.1 ml |
EUR 150 |
HER-2 / c-erbB-2 / neu / CD340; Clone HRB2/451 (Concentrate) |
RA0108-C.5 |
ScyTek Laboratories |
0.5 ml |
EUR 360 |
CD117/c-Kit (Marker for Gastrointestinal Stromal Tumors); Clone C117/370 (Concentrate) |
RA0168-C.1 |
ScyTek Laboratories |
0.1 ml |
EUR 150 |
CD117/c-Kit (Marker for Gastrointestinal Stromal Tumors); Clone C117/370 (Concentrate) |
RA0168-C.5 |
ScyTek Laboratories |
0.5 ml |
EUR 360 |
Human PSA ELISA Combo Kit (Free + Total) |
PRB-5049-C |
Cell Biolabs |
96 assays |
EUR 999.6 |
S-Adenosylmethionine (SAM) and S-Adenosylhomocysteine (SAH) ELISA Combo Kit |
STA-671-C |
Cell Biolabs |
96 assays |
EUR 1040.4 |
Description: S-adenosylmethionine (SAM) is a substrate for methyl transfers to various biomolecules that yields S-adenosylhomocysteine (SAH). SAH is then hydrolyzed to homocysteine and adenosine, which is converted to methionine, and ultimately back to SAM. SAH can act as a methylation inhibitor, therefore the SAM/SAH ratio, or methylation potential, is important for maintaining proper methylation in the cell. Our S-Adenosylmethionine (SAM) and S-Adenosylhomocysteine (SAH) ELISA Combo Kit is designed for detection and quantitation of both SAM and SAH in plasma, serum, lysates, or biological fluid samples. This assay is a competitive ELISA where samples and an anti-SAM or anti-SAH antibody are added to a plate coated with a SAM or SAH conjugate. The sample and conjugate compete for antibody binding, which generates a reverse curve. Samples with high SAM and SAH levels will bind the majority of the antibody, which gets washed away and results in a low OD, while samples with low SAM and SAH levels will leave more antibody available to bind to the conjugate, producing a high signal. |
OxiSelect Aldehyde-Induced DNA Damage ELISA Combo Kit (Ethenoadenosine / Ethenocytidine Quantitation) |
STA-820-C |
Cell Biolabs |
96 assays |
EUR 957.6 |
Description: The OxiSelect Aldehyde-Induced DNA Damage ELISA Combo Kit (Ethenoadenosine / Ethenocytidine Quantitation) is a competitive ELISA kit allowing the quantitation of ethenoadenosine or ethenocytidine adducts in DNA isolated from cells or tissues. Samples and standards are added to a provided microplate preabsorbed with etheno-damaged DNA. A primary antibody is added and binds competitively to ethenoadenosine in the unknown sample or to the etheno adduct in the DNA coated on the plate. After washing a secondary antibody is added. A low signal means most of the primary antibody was bound to the unknown, indicating a high level of etheno adducts in the sample. Each combo kit can perform up to 96 assays combined for ethenoadenosine and ethenocytidine. The two targets are assayed in separate wells, but any well on the provided plate may be used for either target in any ratio (e.g. 64 wells for ethenoadenosine and 32 wells for ethenocytidine, or 48 wells for each). |
OxiSelect UV-Induced DNA Damage ELISA Combo Kit (CPD / 6-4PP Quantitation) |
STA-322-C |
Cell Biolabs |
96 assays |
EUR 992.4 |
Description: Our OxiSelect UV-Induced DNA Damage ELISA Combo Kit measures the formation of both CPD and 6-4PP structures in DNA isolated from cells or tissues. Standards or unknown DNA samples are first heat denatured before adsorbed onto a 96-well DNA binding plate. The sample or standard are then probed with an anti-6-4PP or CPD antibody, followed by an HRP conjugated secondary antibody. CPD and 6-4PP structures are assayed on the same plate but in separate wells. |
Canine Cholecystokinin (CCK) ELISA Kit |
DLR-CCK-c-48T |
DL Develop |
48T |
EUR 632.4 |
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine Cholecystokinin (CCK) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Canine Cholecystokinin (CCK) ELISA Kit |
DLR-CCK-c-96T |
DL Develop |
96T |
EUR 825.6 |
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine Cholecystokinin (CCK) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Canine Clusterin (CLU) ELISA Kit |
DLR-CLU-c-48T |
DL Develop |
48T |
EUR 658.8 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Clusterin (CLU) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Canine Clusterin (CLU) ELISA Kit |
DLR-CLU-c-96T |
DL Develop |
96T |
EUR 861.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Clusterin (CLU) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Canine Calcitonin (CT) ELISA Kit |
DLR-CT-c-48T |
DL Develop |
48T |
EUR 632.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Calcitonin (CT) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Canine Calcitonin (CT) ELISA Kit |
DLR-CT-c-96T |
DL Develop |
96T |
EUR 825.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Calcitonin (CT) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Canine Endoglin (ENG) ELISA Kit |
DLR-ENG-c-48T |
DL Develop |
48T |
EUR 632.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Endoglin (ENG) in samples from serum, plasma or other biological fluids. |
Canine Endoglin (ENG) ELISA Kit |
DLR-ENG-c-96T |
DL Develop |
96T |
EUR 825.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Endoglin (ENG) in samples from serum, plasma or other biological fluids. |
Canine Erythropoietin (EPO) ELISA Kit |
DLR-EPO-c-48T |
DL Develop |
48T |
EUR 632.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Erythropoietin (EPO) in samples from serum, plasma or other biological fluids. |
Canine Erythropoietin (EPO) ELISA Kit |
DLR-EPO-c-96T |
DL Develop |
96T |
EUR 825.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Erythropoietin (EPO) in samples from serum, plasma or other biological fluids. |
Canine Gastrin (GT) ELISA Kit |
DLR-GT-c-48T |
DL Develop |
48T |
EUR 658.8 |
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine Gastrin (GT) in samples from serum, plasma or other biological fluids. |
Canine Gastrin (GT) ELISA Kit |
DLR-GT-c-96T |
DL Develop |
96T |
EUR 861.6 |
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine Gastrin (GT) in samples from serum, plasma or other biological fluids. |
Canine Adrenomedullin (ADM) ELISA Kit |
DLR-ADM-c-48T |
DL Develop |
48T |
EUR 632.4 |
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine Adrenomedullin (ADM) in samples from serum, plasma or other biological fluids. |
Canine Adrenomedullin (ADM) ELISA Kit |
DLR-ADM-c-96T |
DL Develop |
96T |
EUR 825.6 |
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine Adrenomedullin (ADM) in samples from serum, plasma or other biological fluids. |
Canine Adiponectin (ADP) ELISA Kit |
DLR-ADP-c-48T |
DL Develop |
48T |
EUR 568.8 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Adiponectin (ADP) in samples from serum, plasma or other biological fluids. |
Canine Adiponectin (ADP) ELISA Kit |
DLR-ADP-c-96T |
DL Develop |
96T |
EUR 736.8 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Adiponectin (ADP) in samples from serum, plasma or other biological fluids. |
Canine Albumin (ALB) ELISA Kit |
DLR-ALB-c-48T |
DL Develop |
48T |
EUR 423.6 |
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine Albumin (ALB) in samples from serum, plasma or other biological fluids. |
Canine Albumin (ALB) ELISA Kit |
DLR-ALB-c-96T |
DL Develop |
96T |
EUR 537.6 |
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine Albumin (ALB) in samples from serum, plasma or other biological fluids. |
Canine Osteocalcin (OC) ELISA Kit |
DLR-OC-c-48T |
DL Develop |
48T |
EUR 632.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Osteocalcin (OC) in samples from serum, plasma, tissue homogenates or other biological fluids. |
Canine Osteocalcin (OC) ELISA Kit |
DLR-OC-c-96T |
DL Develop |
96T |
EUR 825.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Osteocalcin (OC) in samples from serum, plasma, tissue homogenates or other biological fluids. |
Canine Osteopontin (OPN) ELISA Kit |
DLR-OPN-c-48T |
DL Develop |
48T |
EUR 632.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Osteopontin (OPN) in samples from serum, plasma, tissue homogenates or other biological fluids. |
Canine Osteopontin (OPN) ELISA Kit |
DLR-OPN-c-96T |
DL Develop |
96T |
EUR 825.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Osteopontin (OPN) in samples from serum, plasma, tissue homogenates or other biological fluids. |
Canine Orexin (OX) ELISA Kit |
DLR-OX-c-48T |
DL Develop |
48T |
EUR 658.8 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Orexin (OX) in samples from serum, plasma, tissue homogenates or other biological fluids. |
Canine Orexin (OX) ELISA Kit |
DLR-OX-c-96T |
DL Develop |
96T |
EUR 861.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Orexin (OX) in samples from serum, plasma, tissue homogenates or other biological fluids. |
Canine Renin (REN) ELISA Kit |
DLR-REN-c-48T |
DL Develop |
48T |
EUR 632.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Renin (REN) in samples from serum, plasma, tissue homogenates or other biological fluids. |
Canine Renin (REN) ELISA Kit |
DLR-REN-c-96T |
DL Develop |
96T |
EUR 825.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Renin (REN) in samples from serum, plasma, tissue homogenates or other biological fluids. |
Canine Haptoglobin (Hpt) ELISA Kit |
DLR-Hpt-c-48T |
DL Develop |
48T |
EUR 632.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Haptoglobin (Hpt) in samples from serum, plasma or other biological fluids. |
Canine Haptoglobin (Hpt) ELISA Kit |
DLR-Hpt-c-96T |
DL Develop |
96T |
EUR 825.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Haptoglobin (Hpt) in samples from serum, plasma or other biological fluids. |
Canine Insulin (INS) ELISA Kit |
DLR-INS-c-48T |
DL Develop |
48T |
EUR 748.8 |
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine Insulin (INS) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Canine Insulin (INS) ELISA Kit |
DLR-INS-c-96T |
DL Develop |
96T |
EUR 985.2 |
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine Insulin (INS) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Canine Leptin (LEP) ELISA Kit |
DLR-LEP-c-48T |
DL Develop |
48T |
EUR 632.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Leptin (LEP) in samples from serum, plasma or other biological fluids. |
Canine Leptin (LEP) ELISA Kit |
DLR-LEP-c-96T |
DL Develop |
96T |
EUR 825.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Leptin (LEP) in samples from serum, plasma or other biological fluids. |
Canine Lactoferrin (LTF) ELISA Kit |
DLR-LTF-c-48T |
DL Develop |
48T |
EUR 632.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Lactoferrin (LTF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Canine Lactoferrin (LTF) ELISA Kit |
DLR-LTF-c-96T |
DL Develop |
96T |
EUR 825.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Lactoferrin (LTF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Canine Thrombomodulin (TM) ELISA Kit |
DLR-TM-c-48T |
DL Develop |
48T |
EUR 574.8 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Thrombomodulin (TM) in samples from plasma. |
Canine Thrombomodulin (TM) ELISA Kit |
DLR-TM-c-96T |
DL Develop |
96T |
EUR 745.2 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Thrombomodulin (TM) in samples from plasma. |
Canine Thrombopoietin (TPO) ELISA Kit |
DLR-TPO-c-48T |
DL Develop |
48T |
EUR 632.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Thrombopoietin (TPO) in samples from serum, plasma or other biological fluids. |
Canine Thrombopoietin (TPO) ELISA Kit |
DLR-TPO-c-96T |
DL Develop |
96T |
EUR 825.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Thrombopoietin (TPO) in samples from serum, plasma or other biological fluids. |
Canine Tryptase (TPS) ELISA Kit |
DLR-TPS-c-48T |
DL Develop |
48T |
EUR 658.8 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Tryptase (TPS) in samples from serum, plasma, tissue homogenates or other biological fluids. |
Canine Tryptase (TPS) ELISA Kit |
DLR-TPS-c-96T |
DL Develop |
96T |
EUR 861.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Tryptase (TPS) in samples from serum, plasma, tissue homogenates or other biological fluids. |
Canine Transferrin (TRF) ELISA Kit |
DLR-TRF-c-48T |
DL Develop |
48T |
EUR 414 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Transferrin (TRF) in samples from serum, plasma or other biological fluids. |
Canine Transferrin (TRF) ELISA Kit |
DLR-TRF-c-96T |
DL Develop |
96T |
EUR 524.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Transferrin (TRF) in samples from serum, plasma or other biological fluids. |
Canine Ubiquitin (Ub) ELISA Kit |
DLR-Ub-c-48T |
DL Develop |
48T |
EUR 632.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Ubiquitin (Ub) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Canine Ubiquitin (Ub) ELISA Kit |
DLR-Ub-c-96T |
DL Develop |
96T |
EUR 825.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Canine Ubiquitin (Ub) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Canine Leptin (LEP) ELISA Kit |
RD-LEP-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 639.6 |
Canine Leptin (LEP) ELISA Kit |
RD-LEP-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 888 |
Canine Lactoferrin (LTF) ELISA Kit |
RD-LTF-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 639.6 |
Canine Lactoferrin (LTF) ELISA Kit |
RD-LTF-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 888 |
Canine Osteocalcin (OC) ELISA Kit |
RD-OC-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 639.6 |
Canine Osteocalcin (OC) ELISA Kit |
RD-OC-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 888 |
Canine Osteopontin (OPN) ELISA Kit |
RD-OPN-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 639.6 |
Canine Osteopontin (OPN) ELISA Kit |
RD-OPN-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 888 |
Canine Renin (REN) ELISA Kit |
RD-REN-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 639.6 |
Canine Renin (REN) ELISA Kit |
RD-REN-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 888 |
Canine Thrombomodulin (TM) ELISA Kit |
RD-TM-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 573.6 |
Canine Thrombomodulin (TM) ELISA Kit |
RD-TM-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 794.4 |
Canine Thrombopoietin (TPO) ELISA Kit |
RD-TPO-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 639.6 |
Canine Thrombopoietin (TPO) ELISA Kit |
RD-TPO-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 888 |
Canine Tryptase (TPS) ELISA Kit |
RD-TPS-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 668.4 |
Canine Tryptase (TPS) ELISA Kit |
RD-TPS-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 930 |
Canine Transferrin (TRF) ELISA Kit |
RD-TRF-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 392.4 |
Canine Transferrin (TRF) ELISA Kit |
RD-TRF-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 534 |
Canine Ubiquitin (Ub) ELISA Kit |
RD-Ub-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 639.6 |
Canine Ubiquitin (Ub) ELISA Kit |
RD-Ub-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 888 |
Canine Adrenomedullin (ADM) ELISA Kit |
RDR-ADM-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 668.4 |
Canine Adrenomedullin (ADM) ELISA Kit |
RDR-ADM-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 928.8 |
Canine Adiponectin (ADP) ELISA Kit |
RDR-ADP-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 591.6 |
Canine Adiponectin (ADP) ELISA Kit |
RDR-ADP-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 819.6 |
Canine Albumin (ALB) ELISA Kit |
RDR-ALB-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 420 |
Canine Albumin (ALB) ELISA Kit |
RDR-ALB-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 574.8 |
Canine Cholecystokinin (CCK) ELISA Kit |
RDR-CCK-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 668.4 |
Canine Cholecystokinin (CCK) ELISA Kit |
RDR-CCK-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 928.8 |
Canine Haptoglobin (Hpt) ELISA Kit |
RD-Hpt-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 639.6 |
Canine Haptoglobin (Hpt) ELISA Kit |
RD-Hpt-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 888 |
Canine Adrenomedullin (ADM) ELISA Kit |
RD-ADM-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 639.6 |
Canine Adrenomedullin (ADM) ELISA Kit |
RD-ADM-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 888 |
Canine Adiponectin (ADP) ELISA Kit |
RD-ADP-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 566.4 |
Canine Adiponectin (ADP) ELISA Kit |
RD-ADP-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 783.6 |
Canine Albumin (ALB) ELISA Kit |
RD-ALB-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 403.2 |
Canine Albumin (ALB) ELISA Kit |
RD-ALB-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 549.6 |
Canine Cholecystokinin (CCK) ELISA Kit |
RD-CCK-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 639.6 |
Canine Cholecystokinin (CCK) ELISA Kit |
RD-CCK-c-96Tests |
Reddot Biotech |
96 Tests |
EUR 888 |
Canine Clusterin (CLU) ELISA Kit |
RD-CLU-c-48Tests |
Reddot Biotech |
48 Tests |
EUR 668.4 |
We searched Medline, Embase, the Cochrane Library, and gray literature sources as much as August 2021 for randomized managed trials (RCTs) that in contrast sotagliflozin with placebo or different antidiabetic brokers in sufferers with sort 2 diabetes. Our main final result was change in HbA1c from baseline.